Subscribe now

Health

The big unanswered questions about the covid-19 coronavirus

Despite studying the SARS-CoV-2 virus for five years, scientists still have questions, from the extent to which it can survive and mutate in animals to the thorny argument over its origins

By Graham Lawton

1 January 2025

The coronavirus was first detected at the Huanan Seafood Wholesale Market in Wuhan, China

HECTOR RETAMAL/AFP via Getty Images

When the first signs of an unknown virus began showing up in Wuhan, China, in December 2019, scientists raced to understand what was happening. In the five years since, they haven’t stopped running, with over 1 million papers published about SARS-CoV-2 and covid-19. Yet despite this outpouring, some big scientific questions about the virus remain.

Is the virus lurking within wildlife?

Early in the pandemic, it became clear that the coronavirus could jump from humans into other animals and back…

Sign up to our weekly newsletter

Receive a weekly dose of discovery in your inbox! We'll also keep you up to date with New Scientist events and special offers.

Sign up

To continue reading, subscribe today with our introductory offers